An Integrative Analysis of Metabolome and Transcriptome Reveals the Molecular Regulatory Mechanism of the Accumulation of Flavonoid Glycosides in Different Cyclocarya paliurus Ploidies

Cyclocarya paliurus (Batal) Iljinskaja is mainly used for harvesting leaves as materials tea production and ingredients the food industry. As its most important component, contents of total or specific flavonoids are supposed to vary at different ploidy levels. In present study, two levels C. study their metabolome transcriptome profiles. Though content in that were collected September (the main season) presented insignificant differences between ploidies, flavonoid glucuronides significantly accumulated tetraploid paliurus. Several structural genes related biosynthesis these expressed differentially, including PAL, 4CL, CHS, CpUGTs. A weighted gene co-expression network analysis (WGCNA) revealed nine highly correlated with glucuronide contents. Furthermore, 3 CpMYB39 CpUGT71 associated this accumulation These results can provide a new perspective on how polyploid alter quantitative qualitative patterns secondary metabolite